This article focuses on the history of the Luther House, from its beginning in 1504, its contents including Luther’s room, to the establishment of a museum and archives under its current Director, Dr. Martin Treu, which today has approximately 15,000 printed documents from the 16th through the 18th century among which are 90% of first editions of Luther’s publications. In addition there are 6,000 manuscripts from the 11th through the 19th centuries; a Reformation history coin and medallion collection; 10,000 etchings, woodcuts and drawings from the 16th to the 20th centuries; 135 paintings; 48 incunabulum; as well as individual valuable artifacts.